Key Highlights
- New research shows there is a strong link between changes in hormones and adolescent idiopathic scoliosis during puberty.
- High estrogen levels may be very important in the progression of scoliosis curves in teen girls.
- Adolescent girls have a higher risk for idiopathic scoliosis, and the condition can get worse faster. This is likely because of hormonal differences.
- A hormone imbalance during a growth spurt can cause bone growth to be uneven, which can then lead to spinal curvature.
- By learning more about these hormone links, new treatment plans are now being made, such as the ScoliSMART scoliosis boot camp. These go beyond just watching the curve and offer new hope for adolescent girls with idiopathic scoliosis.

Introduction
Have you ever thought about why idiopathic scoliosis usually starts or gets worse during the teen years? The reason could be in all the things happening inside the body at that time. Puberty is a time when bone growth speeds up and hormones are also changing. Recent studies show that these shifting hormones have a significant role in how spinal curvature starts and how the progression of scoliosis happens. This new information is changing the way we look at diagnosis and scoliosis treatment, giving people better treatment options.
Understanding Scoliosis in Teen Girls
Scoliosis is not just about the spine being curved. It is a condition that is shaped by many things. This is true during puberty, a time when the body starts to grow fast. Changes in hormones can affect the way the spine grows. For many teens, this time is when scoliosis progression gets quicker.
Let’s find out what scoliosis is. We will also see why it gets worse so fast when people are in their teenage years. You will learn who is most at risk for getting it. This will help you better know the special problems that scoliosis patients go through when they are young.
What Is Adolescent Idiopathic Scoliosis?
Scoliosis is when the spine curves to the side, and this curve is 10 degrees or more. The most common type is idiopathic scoliosis. This means doctors do not know a single main cause for it. A lot of the time, it shows up in children and teens. Most cases seen in adolescent idiopathic scoliosis patients are from this type. This spinal deformity can also affect how the central nervous system talks to the rest of the body in scoliosis patients.
Research shows that hormone imbalances may be linked to adolescent idiopathic scoliosis in teen girls. Hormones, like estrogen, have a big effect on bone growth. A study says that there can be a problem with how estrogen is used in the body as a girl grows. This could be one reason that adolescent idiopathic scoliosis starts.
Hormones can change the way the spine grows. This is why it is important to check the spine in young people. Finding problems early can help control curve progression before it gets worse. It is also good to know how hormones and changes in the spine are connected. This helps us give better care.
Prevalence and Risk Factors Unique to Teen Girls
In cases of scoliosis, teen girls get this problem more often than boys. Their curves also tend to get worse more often. So, why does this happen? The main reason looks to be hormone levels. Boys and girls have different hormone patterns when they go through puberty, and this seems to play a big part in the gap.
A 2024 study shows the condition called adolescent idiopathic scoliosis happens more often in girls. This change often matches up with puberty. This points to a link with hormones in the body. Estrogen is a hormone that is important for bone growth. If a girl’s body does not use estrogen the way it should, this can lead to uneven bones in the spine. This can raise the risk of scoliosis.
Keywords: idiopathic scoliosis, adolescent idiopathic scoliosis, bone growth, risk of scoliosis
Some of the main things that can put adolescent girls at higher risk are:
- During puberty, there will be higher estrogen levels.
- How the body uses estrogen for bone growth is important.
- The growth spurt depends on when it happens and how strong it is. This comes from changes in hormones.
Differences in Scoliosis Progression Between Girls and Boys
The progression of scoliosis is not the same for girls and boys. Girls have a much higher chance that their spinal curve will get worse. This is why teen girls are more likely than boys to go through hormone-related scoliosis progression. The way hormones change in puberty is very different for each gender.
For girls, when there is more estrogen in the body, it mostly causes the growth spurt and helps bones grow. If the body does not handle this hormone well, bone development can get off track. This can make the spinal curve worse. Girls who are idiopathic scoliosis patients often see adolescent idiopathic scoliosis get worse fast during this time of bone growth. The spinal curve may go up more quickly in these adolescent idiopathic scoliosis patients.
Boys go through puberty because of more testosterone in the body. This time is also marked by fast growth. But the hormones that are active in boys are not the same as in girls. They offer more safety against strong curve progression. This difference in hormones is important. Because of this, keeping a close eye on spinal health is extra important for girls in their teen years.
The Role of Hormones During Puberty
Puberty starts when the body’s hormones change a lot. These hormones cause many changes. A child’s body grows and turns into an adult’s body. Some hormones make kids grow fast. Others can cause their moods to shift. For teens who already have a chance of getting scoliosis, these changes in hormone levels can make it start or get worse.
When the balance of these strong sex hormones is off, it can change how bones grow. This may play a part in causing a spinal curve to get worse. Looking at the main hormonal factors helps us see how they link bone growth to problems like scoliosis and a spinal curve.
Key Hormones Involved in Female Development
Many important hormones play a big part in puberty. They also have a strong effect on spinal health, bone growth, and scoliosis. Estrogen is a key hormone for girls. It helps bones grow and develop. If estrogen levels are not balanced, it is more likely to lead to scoliosis. Progesterone works with estrogen too. Studies show that girls who have scoliosis often show changes in their progesterone levels. Testosterone and estradiol, which is a strong type of estrogen, are linked with scoliosis getting worse in teenage girls.
The main hormones that impact puberty and spine health are:
- Estrogen: This hormone helps bone growth and helps bones grow up and get stronger.
- Testosterone: This hormone helps with bone density.
- Growth Hormone (GH): This hormone helps with overall bone growth.
During puberty, hormone levels go up fast, especially estrogen in girls. This changes the body quickly and can raise the risk of scoliosis. When hormone levels change quickly, the spine can grow unevenly. This may cause it to twist or curve. The body tries to keep up but sometimes cannot stop these changes. Because of this, the teenage years are an important time when scoliosis progression can happen, mostly because of these hormone shifts.
The Interplay Between Hormones and Growth Spurts
The adolescent growth spurt is when scoliosis often first shows up or gets worse quickly. This does not happen by chance. The growth spurt is caused by a big change in hormone levels, and this puts a lot of stress on the spine. During this time, parts of the spine may not grow at the same speed, which can lead to the development of a spinal curvature.
Hormone imbalances can have a big impact in adolescent idiopathic scoliosis for teen girls at this age. Hormones help with bone growth. When these are not balanced, bone can grow in a different way. The front of the spine may grow at a different speed than the back. Sometimes, the signals to bone cells are not right. This can change how bones develop.
Think about one side of the spine growing quicker than the other. The spine will start to bend and twist to match this uneven growth. This happens because the bone formation is not even on both sides. That is why it’s important to have the right mix of hormones in the body. A balanced hormonal environment helps keep the spine straight, especially during the teenage years when so many changes are happening.
Estrogen’s Effect on Scoliosis Progression
Estrogen is important for bone growth and good spinal health. It helps the body form strong bones and makes sure they develop the right way. When everything works in balance, estrogen helps keep bone density at a good level. But, if the effects of estrogen are not right, it can affect the development of scoliosis and bone health.
When estrogen levels are too high or the body does not use it in the right way, this can mix up how things are supposed to work. This is a big idea in why curve progression in scoliosis might speed up.
How Estrogen Influences Bone Growth and the Spine
Estrogen plays a big role in bone growth and health. It helps close the growth plates and keeps bone density strong. But, when there is too much or too little estrogen in teenage girls, this can get in the way of normal spine development. This change in hormone levels can make the bones in the back grow at different rates. Because of this, the spine can twist or bend, which people know as scoliosis.
More and more research is showing that there is a link between abnormal estrogen levels and adolescent idiopathic scoliosis. Studies say that girls with scoliosis that gets worse often have higher estrogen levels or problems with how their bodies handle estrogen, compared to girls whose scoliosis is not changing. While estrogen is important for good bone health, too much or not handling it right can have an effect. It can lead to spine problems in young people during these years.
This research is important to know why some teens are more at risk. Here is a look at what some studies have found:
| Hormone / Factor | Proposed Role in Scoliosis |
| Estrogen | Influences bone growth and maturation. Abnormal levels are linked to curve onset and progression. |
| Progesterone | Works with estrogen; imbalances are seen in girls with scoliosis. |
| Gut Microbiota | Plays a role in metabolizing hormones, potentially affecting circulating estrogen levels. |
Why Changes in Estrogen May Trigger Curve Progression
Changes in estrogen can lead to the progression of scoliosis. This happens because it disrupts the balance of bone turnover in the body. Bone turnover is when old bone is taken out and new bone is made. Estrogen helps control this process. It makes sure the bones stay strong and healthy.
When hormone levels change a lot, like in puberty, the body can get out of sync. A teen girl who is more likely to get scoliosis may have high or uneven estrogen. This can make bone formation happen faster in some parts of the spine but not in others.
This uneven growth makes the spinal curve get worse. The spine gets longer and starts to turn so it can match the changes. This leads to a bigger curve in the spine. Estrogen is a hormone that is important for development. If there is not a good balance of estrogen, it can impact the progression of scoliosis in teenage girls. It can make the spinal curve get worse when estrogen levels are not right.
While most people talk about estrogen, other sex hormones also have a part in the development and progression of scoliosis. The hormonal factors at work here are complex. There is a balance between several important chemical messengers in the body. Understanding these connections is important when we make treatment plans that work well for people.
Scoliosis research is still finding out more about how hormones play a role in this condition. What we learn from this can help people get treatments that fit them better. These answers also help in making plans that are not just about the spine but look at other things, too.
Testosterone and Estradiol – Their Roles in the Female Body
Testosterone is the main male hormone, but it is also in the female body. This hormone is important for bone health in both men and women. Estradiol is a very strong type of estrogen. It helps in female development. Both testosterone and estradiol have been connected to idiopathic scoliosis in young people. They play a role in bone health and may be linked to adolescent idiopathic scoliosis.
Are changes in testosterone and estradiol levels linked to scoliosis getting worse in teenage girls? Research says yes. Some studies found that girls who have scoliosis that gets worse can have different amounts of these hormones. These hormone levels are not the same as girls whose scoliosis does not get worse.
When there is not the right balance between estradiol and testosterone, it can impact bone density and how bones grow. This can lead to growth that does not follow a straight path. It may also make a spinal curve worse. So, it is important to check both of these hormones to know more about your risk for scoliosis and problems with the spinal curve. Looking at the whole hormonal picture helps understand bone density and growth changes.
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The Link Between Hormone Imbalances and Curve Severity
Many studies now show that when you have a hormone imbalance, you are more likely to get idiopathic scoliosis. It also means your curve progression can get worse. These hormone problems can make the spine curve more. So, this is an important part to think about when looking at what may cause idiopathic scoliosis and curve progression.
Hormone imbalances have a big effect on adolescent idiopathic scoliosis, especially in teen girls. When the hormone levels in the body are not right, the normal pattern of bone growth can get out of order. Some parts of the spine might grow faster than the others. This can make the spine twist and bend, which people know as idiopathic scoliosis. These changes can bring down bone density and cause problems for the whole skeleton over time. This is why watching hormone levels is important for bone growth and keeping good bone health in teens.
This link is so strong that some researchers have found genetic markers that may make people more likely to feel the effects of changes in hormones. When you put genetics and hormones together, it can speed up scoliosis progression. Because of this, it is very important to spot hormone problems early.
What Current Studies Reveal About Hormonal Pathways
Current clinical studies are looking closely at the role of hormonal factors in the pathogenesis of adolescent idiopathic scoliosis. These studies are now not just seeing a link. They are starting to find out which biological processes lead to idiopathic scoliosis in young people. This work helps us better understand how and why adolescent idiopathic scoliosis may develop.
There is research about how hormones can play a part in scoliosis for teen girls. Some studies look at the hormone receptors that you find on bone cells. Others look at the way the gut microbiome can change how estrogen works in the body. The main goal for all of this work is to find out how these systems work together. They want to know what can help keep the spine safe, or what can make it possible for the spine to start curving.
Key areas of investigation include:
- Genetic Predispositions: Finding out which genes make people more likely to be affected by changes in their hormones.
- Hormone Metabolism: Learning how the body handles and gets rid of hormones, like estrogen.
- Cellular Signaling: Looking at how hormones talk with bone cells and help guide growth.
Puberty and Increased Scoliosis Risk
Puberty is a time when the body changes a lot. It is also when the chance to get a spinal curve, or see it get worse, goes up. A growth spurt in an adolescent, pushed by new hormones, is the main time this can happen. That is when many people first see a spinal curve or see it get bigger.
It is important for parents and teens to know why this happens. When you see signs of curve progression and know about how hormones are part of it, you can get help early. This can make things a lot better for the future.
Why Scoliosis Progresses Faster During Puberty
Scoliosis can get worse fast in puberty because of the adolescent growth spurt. This is a time when the body grows quickly. The growth spurt puts more pressure on the spine. Hormone changes also cause different parts of the spine to grow at different speeds. This can make curve progression in scoliosis happen faster. So, it is important to watch teens closely when they are having a growth spurt.
Some early signs that hormones are affecting the spine are a quick rise in the curve during these growth times, along with irregular or heavy periods. Teens may also feel very tired, go through strong mood swings, or get headaches at the same time as these other symptoms. Knowing these signs helps people act early and manage scoliosis better.
Questions About Menarche, Growth Spurts, and Spinal Changes
The time when a girl has her first menstrual cycle is called menarche. This time is closely linked to her growth spurt. It is also a key point for when her risk of scoliosis is highest. Menarche usually happens after the fastest part of her growth spurt is over. But, it is an important sign for doctors to use when they think about how curve progression might go in the future.
Parents often ask how these events link to spinal curvature and bone formation. They want to know if hormone testing can help predict or monitor scoliosis progression in adolescent girls. The answer is yes. Hormone testing gives a look at the hormonal environment inside the body. It can help find imbalances that may cause curve progression. This may be useful for spotting changes in a girl’s spine over time.
It’s important to know how the menstrual cycle, growth spurt, and changes in the spine are linked. This helps healthcare providers see the times when the risk is highest. Then, they can adjust monitoring and treatment plans as needed. A proactive approach like this can really help with managing scoliosis.
Reviewing Recent Scientific Studies
You do not need to just trust what we say. The scientific community is looking into how hormones and scoliosis are connected. There are many clinical studies and recent studies on this link. People are now starting to see scoliosis as not just a problem with the bones. It is more about the whole body, including biology and how it works.
This scoliosis research is leading the way for new ways to care for adolescent idiopathic scoliosis. Let’s look at some key findings from recent studies to show why this connection is so important.
A helpful review was published in 2023 by MDPI about hormones and how they can be linked to scoliosis in teen girls. This review, called “Hormonal Dysregulation, Gut Dysbiosis and Abnormal Weight Status in the Pathogenesis of Adolescent Idiopathic Scoliosis,” talked about how sex hormones, gut health, and changes to body weight might all be connected to adolescent idiopathic scoliosis. This type of scoliosis research helps people who want to know what plays a part in the pathogenesis of adolescent idiopathic scoliosis and what can cause scoliosis progression. Anyone interested in idiopathic scoliosis should look at this information because it gives new ideas about why this problem starts and how the body works during these changes.
The study shows that hormones are a big part of the story when it comes to scoliosis. Hormones are not just something extra. They play an important role. The study looked at hormones like estrogen and progesterone. It showed how these hormones can help start and move the condition forward.
The review also talked about new research. It said that the gut microbiome may play a part in how hormones work in the body. This can then change the risk of getting scoliosis. These clinical studies show that treatment should not just focus on one thing. A multi-faceted approach is needed for better care.
A 2024 study, “The Role of Hormonal and Adipose Tissue-Related Biomarkers in the Pathogenesis of Adolescent Idiopathic Scoliosis,” gave us more to know about hormonal factors in adolescent idiopathic scoliosis. The research looked for certain hormonal biomarkers that may help find out which cases of idiopathic scoliosis will see more curve progression and what plays a role in the pathogenesis of adolescent idiopathic scoliosis.
The study found that adolescent idiopathic scoliosis happens more in girls. It often gets worse during puberty. This shows that hormones might play a big part in this condition. The researchers looked at the role of several hormones and at signals that come from fat in the body. The findings show that idiopathic scoliosis has many causes and is not linked to just one thing.
One important thing to remember is that the amount of a hormone is not the only thing that matters. It is also about how the body makes it, uses it, and reacts to it. If we can find a good way to measure this, it could help us make better tests and treatments for teens who may be at risk.
These recent studies change the way we see scoliosis in adolescent girls. The focus is moving from seeing it as only a problem with the backbone, to seeing it as a complex issue with deep biological causes. Now, there is more attention on hormonal factors, which may play a big role in this disease.
This scoliosis research helps us do more than just “watch and wait.” When we know which hormonal pathways are at play, we can find better treatment options. These treatments work on the root causes of the problem, not just the signs you see.
For parents and teens, this brings hope. It makes room for care that fits the person. It also looks at each person’s special hormone levels. Now, there are new ways to treat these issues. These treatments help people feel better for a long time and improve the quality of life.
Integrating the ScoliSMART Approach
At ScoliSMART, we help people with more than just the curve. We look at how the whole person is doing. Our new way works better than old methods. It deals with things like hormone levels that affect curve progression. We use smart tests to find out what each person needs. Then, we make a plan just for them.
A ScoliSMART doctor will help you with each step. This may have the Scoliosis Boot Camp and the ScoliSMART Activity Suit too. You can get started with a no-cost phone consultation to learn more about all this.
How the ScoliSMART Approach Addresses Hormonal Influence
The ScoliSMART way looks at how hormones can make scoliosis worse. A scolismart doctor knows that hormones that are not balanced can make the problem bigger. That is why we use tests to check your hormones. A scolismart doctor uses easy tests that you can do at home. These tests use saliva to help us see what is going on in your body.
This testing helps us step in early. We can fix small problems before they grow bigger. Our healthcare providers use the test results to make personalized treatment plans for you. We do not just sit and wait. We always take proactive steps to help fix the problem.
These plans may have special nutrients to help your body keep its hormone levels in check. We also add our exercises that focus on spinal health. This mix helps your body feel better and keeps your spine strong for a long time.
Functional and Metabolic Testing in ScoliSMART for Teens
Functional or metabolic testing can be used with hormone analysis when looking at scoliosis in teens. At ScoliSMART, we do this testing to get a full picture of a teen’s health. It lets us see hormone levels, and also how the body uses nutrients, manages neurotransmitters, and gets rid of toxins. This helps us understand more about their body and what could be causing problems.
This information is very important for teens who have adolescent idiopathic scoliosis. The results from the tests help us see certain imbalances that can cause the curve to get worse. This does more than give a simple diagnosis. It looks into the main reasons in the body that lead to the condition.
Our testing can show important things that help with treatment:
| Testing Type | What It Reveals |
| Hormone Testing | Identifies imbalances in estrogen, progesterone, and other key hormones. |
| Metabolic Testing | Uncovers nutrient deficiencies or metabolic issues affecting bone health. |
| Neurotransmitter Testing | Assesses brain-spine communication pathways that influence posture. |
How Hormone Testing Guides Personalized Care
Hormone testing can help predict or keep track of scoliosis progression in adolescent girls. At ScoliSMART, hormone testing is a key part of how we give care. The information we get is very important. It lets us do more than just use a basic scoliosis treatment for everyone. We use this to make the treatment plans fit each girl better.
When we know about a teen’s hormonal levels, we can see the times when they may face higher risks. This helps us to step in before problems happen. For example, if testing shows there are high estrogen levels, we can use certain nutrients to help keep hormone levels in a good range.
This way of using data helps us make every part of care fit your needs. This includes what you eat and what exercises you should do. We do this to give your body what it needs to find balance. It also helps support good spine development, instead of just waiting for the problem to get worse.
Scoliosis and the Female Body – Insights From Expert Literature
The link between hormones and spinal curvature goes past just puberty. For female scoliosis patients, changes in hormones can happen during puberty, pregnancy, and menopause. These shifts can affect the curve in the spine. Knowing about these times in life is key for long-term care.
Expert literature gives useful tips on how to deal with these challenges, starting in puberty and going up to the years after menopause. It shares advice that can help women keep their spinal health strong at every stage of life.
“Scoliosis and the Female Body” by Dr. Clayton J. Stitzel
For a full look at this topic, you can read Dr. Clayton J. Stitzel’s book, “Scoliosis and the Female Body: How Puberty, Pregnancy, and Perimenopause Affect Scoliosis Curve Progression,” This book gives new information and links years of scoliosis research with real clinical studies on female hormones. It is a good read if you want to know more about curve progression and what can affect the scoliosis curve in women.
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The book shares why females often get scoliosis more than males. It also talks about how changes in hormones during life can make curve progression worse. The book does not stick to old ideas. It gives you a simple and clear look at the problem, using real evidence to explain curve progression.
Key highlights from the book include:
- Hormones play a big role in how bones grow and develop. They help your body build and keep strong bones. When something changes how your hormones work, it can change how your bones grow.
- There is a link between some hormone problems and the chance of getting scoliosis. A change in hormone levels can make it more likely for some people to get this bend in the spine.
- There are some things you can do to take care of scoliosis during puberty, pregnancy, and perimenopause. Some good steps are to keep good posture, check with your doctor often, do exercises your doctor suggests, and eat foods that keep your bones healthy. You can also ask your doctor if medicine or other care is right for you at these times.
Life Stages: Puberty, Pregnancy, and Perimenopause on Curve Progression
The progression of scoliosis in females often happens during key life changes when there is a shift in hormones. Puberty is the first big time for this. The adolescent growth spurt at puberty causes a lot of fast changes in the body, which makes the progression of scoliosis happen more quickly. A hormone called estrogen plays a big part in this. Estrogen has a big effect on bone growth. That is one big reason why the progression of scoliosis can be worse in teenage girls.
Pregnancy is a time when the hormones in the body change a lot. The hormone called relaxin helps by making the ligaments looser, so it is easier for the baby to be born. But this hormone can also change how steady the spine is. This could make an existing curve in the spine get worse.
Perimenopause and menopause cause less estrogen in the body. When this happens, your bone density can start to go down. This leads to osteoporosis. A weak spine can happen, so your back might be at risk to collapse or shape changes. It is important to know about these risks with curve progression. This helps you care for your bones as you get older.
Practical Tips for Managing Hormones and Scoliosis in Teenage Girls
Handling scoliosis in teenage girls needs a hands-on plan. You should think about both the spine and the hormonal factors. If you take simple steps, you can help balance the hormones. This will also make the quality of life better for them.
While you should always see a healthcare provider, there are some tips that may help. A good treatment plan can include things like physical therapy or using a scoliosis brace. This support can make your care plan better.
- Focus on a Nutrient-Dense Diet: Eating many foods that are whole, have fiber, and are full of important things your body needs can help hormone levels and bone health.
- Encourage Regular, Safe Physical Activity: When your teen joins things like a scoliosis boot camp, they can work their core muscles and fix their posture. This can be done without harming their spine.
- Prioritize Sleep and Stress Management: Making sleep and handling stress a top task is important. These things can change hormone levels a lot. Getting enough sleep can help keep your teen’s hormone levels and their whole body healthy.
Conclusion
To sum up, knowing how hormones affect scoliosis progression in teen girls is very important for parents and those who take care of health. The way hormones like estrogen and testosterone work together during puberty can have a big effect on spinal development and curve progression. Some recent studies, like the ones reviewed in the MDPI research from 2023 and the 2024 hormonal biomarkers study, show how these changes in hormones can impact scoliosis progression and how serious it can get. Also, Dr. Clayton J. Stitzel’s book, “Scoliosis and the Female Body,” explains how different times in a woman’s life, such as puberty and pregnancy, can change scoliosis. Using approaches like ScoliSMART, which includes hormone testing and care planned just for the person, we can help manage this condition in a better way. If you want more support or to know more, you can look for more resources or talk to a professional.
Frequently Asked Questions
Can hormone testing help predict or monitor scoliosis progression in teen girls?
Yes, hormone testing can be a good tool for people with idiopathic scoliosis. In cases of adolescent idiopathic scoliosis, hormone testing can help find the imbalances that happen during a growth spurt. These can cause the spinal curve, or curve progression, to get worse. Hormone testing is not the only way to predict problems, but this scoliosis research method can help doctors keep a closer eye on the curve. It helps make care more personal, so your spinal curve can be managed better.
Are there treatments that target hormones to reduce or slow curve progression?
Yes, some new treatment plans for idiopathic scoliosis take care of changes in hormone levels. These plans do not use fake hormones. Instead, they use certain nutrients. These nutrients help the body balance things like estrogen on its own. By doing this, these treatment plans can slow down curve progression by working with what causes it.
What early signs might show that hormones are influencing scoliosis in teens?
Early signs of this problem can be a fast change in the spinal curvature during a growth spurt. There can also be signs of hormone changes like having periods that are not regular, strong mood swings, or always feeling tired. If you see these in adolescent girls, it can be a clue that hormone levels may take a significant role in the progression of scoliosis.




